LOCUS       HPV72LVX100   452 bp ds-DNA             VRL       16-OCT-1994
DEFINITION  Human papillomavirus, isolate LVX100, partial L1 cds, My09/My11
            region.
ACCESSION   U12485
SOURCE      Human papillomavirus, isolate LVX100 from cervical smear.
  ORGANISM  Human papillomavirus
            Viridae; ds-DNA nonenveloped viruses; Papovaviridae;
            Papillomavirus.
REFERENCE   1  (bases 1 to 452)
  AUTHORS   Ong,C.-K., Bernard,H.-U. and Villa,L.L.
  TITLE     Identification of genomic sequences of three novel human
            papillomaviruses in cervical smears of Amazonian Indians
  JOURNAL   J. Infect. Dis. (1994) In press
  STANDARD  full staff_review
COMMENT     HPVLVX82, HPV72LVX100 and HPVLVX160 were found in cervical smears
            taken from members of isolated Amazonian tribes. The samples were
            PCR-amplified using the MY09/My11 consensus primers, then examined
            in hybridization experiments in order to determine their homology
            with known HPV types. In addition to many previously characterized
            HPV types, these three novel variants were discovered to be more
            than 10% divergent from their closest known relatives, suggesting
            that they may qualify to be considered new types. Although the
            tribes were thought to have been sexually isolated from
            non-Amerindian populations for at least 12,000 years, sequences
            closely related to these novel variants have since been detected in
            other distinct populations.  The authors of [1] state that this may
            be evidence for the hypothesis that papillomavirus types evolved
            before the speciation of Homo sapiens, and consequently before the
            divergence of ethnic groups.  Primer regions are annotated in the
            sequence; information in this region is not accurate due to primer
            degeneracy.  All similarity calculations exclude data from this
            region.

FEATURES             Location/Qualifiers
     CDS             <1..>452
                     /note="putative"
                     /product="major capsid protein"
                     /gene="L1"
                     /note="putative"
                     /codon_start=1
                     /translation="AQGHNNGICWFNELFVTVVDTTRSTNVTICTATASSVSEYTASN
                     FREYLRHTEEFDLQFIFQLCKIHLTPEIMAYLHNMNKALLDDWNFGVVPPPSTSLDDT
                     YRFLQSRAITCQKAATPPPKEDPYANLSFWTVDLKDKFSTDLDQYPLG"
BASE COUNT      116 a     96 c     85 g    155 t
ORIGIN      
        1 gcccagggtc ataataatgg catctgttgg tttaatgagc tttttgtgac agttgtagat
       61 actactcgca gtactaatgt aactatttgt actgccacag cgtcctctgt atcagaatat
      121 acagcttcta attttcgtga gtatcttcgc cacactgagg aatttgattt gcagtttata
      181 tttcaactgt gtaaaattca cttaactcct gaaattatgg cctacttgca caatatgaat
      241 aaggccttat tggatgactg gaattttggt gtggtgcctc ctccttctac cagtttagat
      301 gatacctata ggtttttaca gtctcgtgcc attacctgtc aaaaggctgc cacccctcct
      361 cctaaagaag atccatatgc taacttatcc ttttggactg tggatttaaa ggacaaattt
      421 tccactgact tggatcagta tcctcttgga cg