LOCUS HPV59MY911 452 bp ds-DNA VRL 16-OCT-1994 DEFINITION Human papillomavirus type 59 (HPV-59), partial L1 cds, My09/My11 region. ACCESSION U12496 SOURCE Human papillomavirus type 59 DNA. ORGANISM Human papillomavirus type 59 Viridae; ds-DNA nonenveloped viruses; Papovaviridae; Papillomavirus. REFERENCE 1 (bases 1 to 452) AUTHORS Bernard,H.-U., Chan,S.-Y., Manos,M.M., Ong,C.-K., Villa,L.L., Delius,H., Peyton,C.L., Bauer,H.M., and Wheeler,C.M. TITLE Identification and assessment of known and novel human papillomaviruses by PCR amplification, restriction fragment length polymorphisms, nucleotide sequence, and phylogenetic algorithms JOURNAL J. Infect. Dis. (1994) In press STANDARD full staff_review COMMENT HPV-59 was first isolated from a vulvar intraepithelial neoplasia of the genital mucosa. Cloned HPV-59 DNA was obtained from the Papillomavirus Reference Center, Heidelberg and subsequently sequenced by Dr. H. Delius over the L1 MY09/MY11 segment. HPV-59 and the several other HPV types recently sequenced over this region by Dr. Delius were used as type-specific probes to screen DNA for novel genital HPV types. The screened DNA was obtained from four recent epidemiological studies. Primer regions are annotated in the sequence; information in this region is not accurate due to primer degeneracy. FEATURES Location/Qualifiers CDS <1..>452 /note="putative" /product="major capsid protein" /gene="L1" /note="putative" /codon_start=1 /translation="AQGLNNGICWHNQLFLTVVDTTRSTNLSVCALLLSIPNVYTPTS FKEYARHVEEFDLQFIFQLCKITLTTEVMSYIHNMNTTILEDWNFGVTPPPTASLVDT YRFVQSAAVTCQKDTAPPVKQDPYDKLKFWPVDLKERFSADLDQFPLG" BASE COUNT 130 a 88 c 83 g 151 t ORIGIN 1 gctcagggtt taaacaatgg tatatgttgg cacaatcaat tgtttttaac agttgtagat 61 actactcgca gcaccaatct ttctgtgtgt gctctactac tctctattcc taatgtatac 121 acacctacca gttttaaaga atatgccaga catgtggagg aatttgattt gcagtttata 181 tttcaactgt gtaaaataac attaactaca gaggtaatgt catacattca taatatgaat 241 accactattt tggaggattg gaattttggt gttacaccac ctcctactgc tagtttagtt 301 gacacatacc gttttgttca atctgctgct gtaacttgtc aaaaggacac cgcaccgcca 361 gttaaacagg acccttatga caaactaaag ttttggcctg tagatcttaa ggaaaggttt 421 tctgcagatc ttgatcagtt tcctttggga cg