LOCUS       Rb-BC         127 bp    ds-DNA          PRI       15-DEC-1989
DEFINITION  Human mutant retinoblastoma gene, with a deletion found in a breast
            cancer.
ACCESSION   M27258
KEYWORDS    retinoblastoma protein.
SOURCE      Human breast cancer cell line MB468 DNA, clone Y2.2.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Chordata; Vertebrata; Mammalia; Theria;
            Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 127)
  AUTHORS   Bookstein,R., Lee,E., Peccei,A. and Lee,W.H.
  TITLE     Human retinoblastoma gene: Long-range mapping and analysis of its
            deletion in a breast cancer cell line
  JOURNAL   Mol. Cell. Biol. 9, 1628-1634 (1989)
  STANDARD  full staff_review
COMMENT     The deletion described in [1] spans the 3' end of exon 2 through
            exon 27 and beyond.
FEATURES             Location/Qualifiers
     misc_recomb     70..72
                     /organism="Homo sapiens"
     source          1..127
                     /organism="Homo sapiens"
BASE COUNT       40 a     22 c     25 g     40 t
ORIGIN      Undetermined number of bp after segment 1; chromosome 13q14.2.
        1 agctgaatac tttttacttt tgttagggtt ccctgtgtct cttcctttca tgttgtgcca
       61 cagatgagcc ataacatgaa aatcgctaaa acaagttagg caaagaaaaa ggatttaata
      121 ggcaagt
//