ID HPVMM9 STANDARD; ds-DNA; VRL; 458 bp. XX DE Human papillomavirus isolate MM9, partial L1 cds, My09/My11 region. XX AC U12491 XX DT 16-OCT-1994 XX OS Human papillomavirus DNA recovered from a gential swab sample, isolate OS MM9 (PAP238a). OC Human papillomavirus;Viridae; ds-DNA nonenveloped viruses; OC Papovaviridae;Papillomavirus. XX RN [1] RP 1 - 458 RA Manos,M.M., Waldman,J., Zhang,T. Greer,C., Eichinger,G., Schiffmann,M., RA and Wheeler, C; RT "Epidemiology and partial nucleotide sequence of four novel genital RT human papillomaviruses;" RL J. Infect. Dis. (1994) In press. XX XX Created by HPV database on 21-APR-1995 from GenBank: U12491. XX XX MM9, also known as PAP238a, was isolated from a genital swab sample. XX Samples were obtained from over 500 patients examined at either the XX Shasta/Diablo planned parenthood clinic or at a private practice XX in the state of California over the course of seventeen months. XX Each of the samples were cervical or vulvar/intraoital in origin. XX DNA was PCR amplified over the MY09/MY11 region and subsequently XX sequenced if the HPV digested products yielded unique RFLP patterns. XX This procedure resulted in the identification of four novel HPV XX types: W13B, PAP291, PAP155, and PAP238a, which have subsequently XX been renamed MM4, MM7, MM8, and MM9. Oligonucleotide probes over XX the MY9/MY11 region from these viruses have been reported by XX Hildesheim et al. (J Infect Dis 169: 235-40). These probes were XX used to determine prevalence in different populations. Prevalence XX for each of these viruses was similar to that seen in other XX characterized "intermediate risk" viruses probed for in these XX studies. In addition to anogenital sites, MM9 was identified in a XX periungual carcinoma with multiply infected digits. It should be XX noted that MM4 is extremely similar (90.8%) to novel HPVIS39 (U12481) XX and MM7 is virtually identical to LVX82 (U12487). Primer regions are XX annotated in the sequence; information in this region is not accurate XX due to primer degeneracy. XX XX XX FT KEY Location/Qualifiers FT CDS <1..>458 FT /note="putative" FT /product="major capsid protein" FT /gene="L1" FT /note="putative" FT /codon_start=1 XX SQ SEQUENCE 458 bp; 145 a; 79 c; 84 g; 150 t; gcacagggtc ataataatgg tatttgttgg cataatcaat tatttttaac tgttgtagat 60 actactagaa gcactaattt ttctgtatgt gtaggtacac aggctagtag ctctactaca 120 acgtatgcca actctaattt taaggaatat ttaagacatg cagaagagtt tgatttacag 180 tttgttcttc agttatgtaa aattagttta actactgagg taatgacata tatacattct 240 atgaattcta ctatattgga agagtggaat tttggtctta ccccaccacc gtcaggtact 300 ttagaggaaa catatagata tgtaacatca catgctatta gttgccaacg tcctcaacct 360 cctaaagaaa cagaggaccc atatgccaag ctatcctttt gggatgtaga tcttaaggaa 420 aagttttctg cagaattaga tcagtatccc cttggacg 458