ID   HPVLVX82	STANDARD;	ds-DNA;	VRL;	452 bp.
XX
DE   Human papillomavirus, isolate LVX82, partial L1 cds, My09/My11 region. 
XX
AC   U12487
XX
DT   16-OCT-1994
XX
OS   Human papillomavirus, isolate LVX82 from cervical smear. 
OC   Human papillomavirus;Viridae; ds-DNA nonenveloped viruses; 
OC   Papovaviridae;Papillomavirus.
XX
RN   [1]
RP   1 - 452
RA   Ong,C.-K., Bernard,H.-U. and Villa,L.L;
RT   "Identification of genomic sequences of three novel human 
RT   papillomaviruses in cervical smears of Amazonian Indians;"
RL   J. Infect. Dis. (1994) In press.
XX
XX   Created by HPV database on 21-APR-1995 from GenBank: U12487.
XX
XX   HPVLVX82, HPVLVX100 and HPVLVX160 were found in cervical smears
XX   taken from members of isolated Amazonian tribes. The samples were
XX   PCR-amplified using the MY09/My11 consensus primers, then examined
XX   in hybridization experiments in order to determine their homology
XX   with known HPV types. In addition to many previously characterized
XX   HPV types, these three novel variants were discovered to be more
XX   than 10% divergent from their closest known relatives, suggesting
XX   that they may qualify to be considered new types. Although the
XX   tribes were thought to have been sexually isolated from
XX   non-Amerindian populations for at least 12,000 years, sequences
XX   closely related to these novel variants have since been detected in
XX   other distinct populations.  The authors of [1] state that this may
XX   be evidence for the hypothesis that papillomavirus types evolved
XX   before the speciation of Homo sapiens, and consequently before the
XX   divergence of ethnic groups.  Primer regions are annotated in the
XX   sequence; information in this region is not accurate due to primer
XX   degeneracy.  All similarity calculations exclude data from this
XX   region.
XX
XX
FT  KEY              Location/Qualifiers
FT   CDS             <1..>452
FT                   /note="putative"
FT                   /product="major capsid protein"
FT                   /gene="L1"
FT                   /note="putative"
FT                   /codon_start=1
XX
SQ   SEQUENCE  452 bp;  123 a;  104 c;  87 g;  138 t;
     gcccagggtc ataataatgg catttgttgg tttaatgagt tatttgttac agttgtagat        60
     actacccgca gtaccaatat tactatttca gctgctgcta cacaggctaa tgaatacaca       120
     gcctctaact ttaaggaata cctccgccac accgaggaat atgacttaca ggttatattg       180
     caactttgca aaatacatct tacccctgaa attatggcat acctacatag tatgaatgaa       240
     catttattgg atgagtggaa ttttggcgtg ttaccgcctc cctccaccag ccttgatgat       300
     acctatcgct atttgcagtc ccgtgctatt acctgccaaa agggtccttc cgcccctgcc       360
     cctaaaaagg atccttatga tggccttgta ttttgggagg ttgatttaaa ggacaaacta       420
     tccacagatt tagatcagtt tcctttggga cg                                     452