ID   HPVLVX160	STANDARD;	ds-DNA;	VRL;	0 bp.
XX
DE   Human papillomavirus, isolate LVX160, partial L1 cds, My09/My11 region. 
XX
AC   U12486
XX
DT   16-OCT-1994
XX
OS   Human papillomavirus, isolate LVX160, from cervical smear. 
OC   Human papillomavirus;Viridae; ds-DNA nonenveloped viruses; 
OC   Papovaviridae;Papillomavirus.
XX
RN   [1]
RP   1 - 455
RA   Ong,C.-K., Bernard,H.-U. and Villa,L.L;
RT   "Identification of genomic sequences of three novel human 
RT   papillomaviruses in cervical smears of Amazonian Indians;"
RL   J. Infect. Dis.  (1994) In press.
XX
XX   Created by HPV database on 21-APR-1995 from GenBank: U12486.
XX
XX   HPVLVX82, HPVLVX100 and HPVLVX160 were found in cervical smears
XX   taken from members of isolated Amazonian tribes. The samples were
XX   PCR-amplified using the MY09/My11 consensus primers, then examined
XX   in hybridization experiments in order to determine their homology
XX   with known HPV types. Each of these three novel variants were more
XX   than 10% divergent from their closest known relatives, suggesting
XX   that they may qualify to be considered new types. Although the
XX   tribes were thought to have been sexually isolated from
XX   non-Amerindian populations for at least 12,000 years, sequences
XX   closely related to these novel variants have since been detected in
XX   other distinct populations.  Ong et al. believe this may be 
XX   evidence for the hypothesis that papillomavirus types evolved
XX   before the speciation of Homo sapiens, and consequently before the
XX   divergence of ethnic groups. LVX160 is virtually identical to
XX   HPVL1AE1 (U01535) and to HPVCP141 (U12476).  Primer regions are
XX   annotated in the sequence; information in this region is not
XX   accurate due to primer degeneracy.  All similarity calculations
XX   exclude data from this region.
XX
XX
FT  KEY              Location/Qualifiers
FT   CDS             <1..>455
FT                   /note="putative"
FT                   /product="major capsid protein"
FT                   /gene="L1"
FT                   /note="putative"
FT                   /codon_start=1
XX
SQ   SEQUENCE  0 bp;  142 a;  86 c;  90 g;  137 t;
     gcacagggtc ataataatgg catttgttgg cataaccagt tgtttattac tgtggtggac        60
     actacacgta gtactaattt tacattgtct gcctgcaccg aaacggccat acctgctgta       120
     tatagcccta caaagtttaa ggaatatact aggcatgtgg aggaatatga tttacaattt       180
     atatttcaat tgtgtactat cacattaact gcagacgtta tggcctacat ccatactatg       240
     aatcctgcaa ttttggacaa ttggaatata ggagttaccc ctccaccatc tgcaagcttg       300
     gtggacacgt ataggtattt acaatcagca gctatagcat gtcaaaagga tgctcctaca       360
     cctgaaaaaa aggatcccta tgacgattta aaattttgga atgttgattt aaaggaaaag       420
     tttagtacag aactagatca gtttcctctg ggacg                                  455