ID   MMMDM2	STANDARD;	RNA;	ROD;	1710 bp.
XX
DE   Murine mdm2 mRNA for mdm2 protein. 
XX
AC   X58876
XX
DT   04-OCT-1993
XX
OS   house mouse. 
OC   Mus musculus;Eukaryotae; mitochondrial eukaryotes; Metazoa/Eumycota 
OC   group;Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia; 
OC   Chordata;Vertebrata; Gnathostomata; Osteichthyes; Sarcopterygii; 
OC   Choanata;Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Glires; 
OC   Rodentia;Sciurognathi; Myomorpha; Muridae; Murinae; Mus.
XX
RN   [1]
RP   1 - 1710
RA   George,D.L;
RT   "Direct Submission;"
RL   Submitted (03-APR-1991) to the EMBL/GenBank/DDBJ databases. D.L.George, 
RL   University of Pennsylvania, Dept of Human Genetics, 422Curie Blvd, 
RL   Philadelphia PA 19104-6145, USA.
XX
RN   [2]
RP   1 - 1710
RA   Fakharzadeh,S.S., Trusko,S.P. and George,D.L;
RT   "Tumorigenic potential associated with enhanced expression of a gene 
RT   that is amplified in a mouse tumor cell line;"
RL   EMBO J. 10 (6), 1565-1569 (1991)91224107.
XX
XX   Created by HIV database on  1-NOV-1995 from GenBank: X58876.
XX
XX   MDM2, in addition to E6, interacts with p53 ( Marston et al.,
XX
FT  KEY              Location/Qualifiers
FT   source          1..1710
FT                   /organism="Mus musculus"
FT                   /cell_type="fibroblast-like"
FT                   /cell_line="3T3 DM"
FT                   /clone_lib="lambda ZAPII"
FT                   /clone="B101, D201, pl.4, 702, 3A-5"
FT                   /chromosome="10"
FT                   /map="region C1-C3"
FT   CDS             202..1671
FT                   /gene="mdm2"
FT                   /note="NCBI gi: 53039"
FT                   /codon_start=1
FT                   /product="mdm2 product"
FT                   /translation="MCNTNMSVSTEGAASTSQIPASEQETLVRPKPLLLKLLKSVGAQ
FT                   NDTYTMKEIIFYIGQYIMTKRLYDEKQQHIVYCSNDLLGDVFGVPSFSVKEHRKIYAM
FT                   IYRNLVAVSQQDSGTSLSESRRQPEGGSDLKDPLQAPPEEKPSSSDLISRLSTSSRRR
FT                   SISETEENTDELPGERHRKRRRSLSFDPSLGLCELREMCSGGTSSSSSSSSESTETPS
FT                   HQDLDDGVSEHSGDCLDQDSVSDQFSVEFEVESLDSEDYSLSDEGHELSDEDDEVYRV
FT                   TVYQTGESDTDSFEGDPEISLADYWKCTSCNEMNPPLPSHCKRCWTLRENWLPDDKGK
FT                   DKVEISEKAKLENSAQAEEGLDVPDGKKLTENDAKEPCAEEDSEEKAEQTPLSQESDD
FT                   YSQPSTSSSIVYSSQESVKELKEETQHKDESVESSFSLNAIEPCVICQGRPKNGCIVH
FT                   GKTGHLMSCFTCAKKLKKRNKPCPVCRQPIQMIVLSYFN"
FT   misc_feature    673..684
FT                   /gene="mdm2"
FT                   /note="putative protein kinase A phosphorylation site"
FT   misc_feature    733..847
FT                   /gene="mdm2"
FT                   /note="putative nuclear localisation signal"
XX
SQ   SEQUENCE  1710 bp;  477 a;  397 c;  465 g;  371 t;
     gaggagccgc cgccttctcg tcgctcgagc tctggacgac catggtcgct caggccccgt        60
     ccgcggggcc tccgcgctcc ccgtgaaggg tcggaagatg cgcgggaagt agcagccgtc       120
     tgctgggcga gcgggagacc gaccggacac ccctggggga ccctctcgga tcaccgcgct       180
     tctcctgcgg cctccaggcc aatgtgcaat accaacatgt ctgtgtctac cgagggtgct       240
     gcaagcacct cacagattcc agcttcggaa caagagactc tggttagacc aaaaccattg       300
     cttttgaagt tgttaaagtc cgttggagcg caaaacgaca cttacactat gaaagagatt       360
     atattttata ttggccagta tattatgact aagaggttat atgacgagaa gcagcagcac       420
     attgtgtatt gttcaaatga tctcctagga gatgtgtttg gagtcccgag tttctctgtg       480
     aaggagcaca ggaaaatata tgcaatgatc tacagaaatt tagtggctgt aagtcagcaa       540
     gactctggca catcgctgag tgagagcaga cgtcagcctg aaggtgggag tgatctgaag       600
     gatcctttgc aagcgccacc agaagagaaa ccttcatctt ctgatttaat ttctagactg       660
     tctacctcat ctagaaggag atccattagt gagacagaag agaacacaga tgagctacct       720
     ggggagcggc accggaagcg ccgcaggtcc ctgtcctttg atccgagcct gggtctgtgt       780
     gagctgaggg agatgtgcag cggcggcacg agcagcagta gcagcagcag cagcgagtcc       840
     acagagacgc cctcgcatca ggatcttgac gatggcgtaa gtgagcattc tggtgattgc       900
     ctggatcagg attcagtttc tgatcagttt agcgtggaat ttgaagttga gtctctggac       960
     tcggaagatt acagcctgag tgacgaaggg cacgagctct cagatgagga tgatgaggtc      1020
     tatcgggtca cagtctatca gacaggagaa agcgatacag actcttttga aggagatcct      1080
     gagatttcct tagctgacta ttggaagtgt acctcatgca atgaaatgaa tcctcccctt      1140
     ccatcacact gcaaaagatg ctggaccctt cgtgagaact ggcttccaga cgataagggg      1200
     aaagataaag tggaaatctc tgaaaaagcc aaactggaaa actcagctca ggcagaagaa      1260
     ggcttggatg tgcctgatgg caaaaagctg acagagaatg atgctaaaga gccatgtgct      1320
     gaggaggaca gcgaggagaa ggccgaacag acgcccctgt cccaggagag tgacgactat      1380
     tcccaaccat cgacttccag cagcattgtt tatagcagcc aagaaagcgt gaaagagttg      1440
     aaggaggaaa cgcagcacaa agacgagagt gtggaatcta gcttctccct gaatgccatc      1500
     gaaccatgtg tgatctgcca ggggcggcct aaaaatggct gcattgttca cggcaagact      1560
     ggacacctca tgtcatgttt cacgtgtgca aagaagctaa aaaaaagaaa caagccctgc      1620
     ccagtgtgca gacagccaat ccaaatgatt gtgctaagtt acttcaacta gctgacctgc      1680
     tcacaaaaat agaattttat atttctaact                                       1710